Tone & Slim TONALIN® CLA

CLA is a naturally-occurring fatty acid found most abundantly in beef and dairy fats. Ruminant animals (such as cows) have a special digestive system that converts linoleic acid into CLA, which humans then receive by eating beef and dairy foods. Changes during the past 30 years in how cattle are raised (grain-fed vs. grass-fed), combined with the market trend toward low-fat dairy, have drastically reduced the amount of CLA humans acquire through diet. As a result, most of us aren’t receiving the health benefits CLA offers.

Tonalin is made from a confidential and proprietary process to convert the linoleic acid of safflower oil, a pure and natural vegetable oil, into CLA. The unique processing for TONALIN CLA optimizes its two active isomers and yields a safe, efficacious natural source product.

Tone & Slim TONALIN CLA and Body Weight Management

Clinical and laboratory research indicates that TONALIN CLA helps reduce body fat while maintaining or increasing lean body mass.* Seven clinical studies have been conducted to measure the safety and efficacy of TONALlN CLA, including one long-term study.

In a recent clinical trial, overweight subjects taking TONALIN CLA for one year, without changing their diet and exercise habits, had a 9% reduction in body fat and a 2% increase in lean body mass compared to the placebo group.

In a short-term study, healthy subjects of normal weight experienced a 20% reduction in body fat when CLA was combined with 90 minutes of exercise three times a week (Thom et al., 2001).

Additional studies lasted from 4 weeks to 6months and included men, women, healthy and/or overweight individuals. The CLA intake in these studies ranged from 1.8g-6.8gTONALIN CLA per day. The results consistently demonstrated a significant decrease in body fat with TONALIN CLA compared to the placebo groups .

Mechanism for Decreasing Body Fat Mass

•  Scientific knowledge to date indicates that CLA has two main sites of action: the adipocytes (the principle site where fat is stored) and the skeletal muscle cells (the principle site where fat is burned for energy).

•  Studies have shown that CLA decreases the transfer of fat from the blood into the fat cells (adipocytes) for storage. Simultaneously, CLA also stimulates lipolysis, or the breakdown of stored fat in the fat cells (Park et al., 1997). *

•  CLA has also been shown to decrease the number of existing fat cells (Evans et al.,2000).*

•  Additional studies have demonstrated that CLA is able increase energy production from fat.

Summary

Tone & Slim Tonalin CLA decreases body fat mass by*:

•  Decreasing the amount of fat that is stored after eating
•  Increasing the rate of fat breakdown in fat cells
•  Increasing the rate of fat metabolism decreasing the total number of fat cells
•  Together, these four actions lead to a decrease in adipocyte number and size, which consequently results in body fat mass decrease.

* As part of a calorie controlled diet.

References

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Blankson, H., Stakkestad, J.A., Fagertun, H.,Thom, E., Wadstein, J., and Gudmundsen, 0. Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J Nutr. 2000; 1 30,2943-2948.
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